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Missense3D-PTM^DB is a comprehensive resource which allows users to explore millions of variants, post-translational modifications (PTMs), and topology information, if any, for the collection of canonical proteins within the human proteome (~20,000). Users can visualize these features on a 3D AlphaFold model for their protein of interest by simply providing (1) a gene name or UniProt ID, (2) a position within the canonical UniProt protein sequence, and (3) the wild type residue at that position. Click here for more information on datasets used within Missense3D-PTM and additional documentation.