Last database update: June, 2019

Missense3D-DB contains single amino acid variants (SAVs) from Humsavar, ClinVar and gnomAD mapped to PDB structures and Phyre models

Variants were extracted from UniProt knowledgebase and Humsavar version: 2019_06
Numbers of SAVs in the database: 3,960,015
Number of proteins: 16,477

Humsavar variants: 49,480
ClinVar variants: 82,881
dbSNP variants (including gnomAD): 3,865,525

Variants mapped to PDB structures: 1,110,833
Variants mapped to Phyre models: 2,849,182
(Note: All Phyre models are above 95% confidence with more than 30 residues.)