Test and Training Datasets


Variants


The dataset of 2,078 disease-causing and 1,060 neutral variants studied in our paper (“Missense3D-TM: predicting the effect of missense variants in helical transmembrane protein regions using 3D protein structures” Hanna G, Khanna T, Islam SA, David A and Sternberg MJE) is available here:

1 List of 794 Test variants Download CSV
2 List of 2,344 Training variants Download CSV

Results


Precomputed Missense3D results for the dataset used in our paper are available here:

1 List of 794 Test results Download CSV
2 List of 2,344 Training results Download CSV

Structures and Mappings


Structure files and mappings for the dataset used in our paper are available here (please be aware these download files are very large and even larger when unzipped):

1 193 model and experimental structure files for Test dataset (19 MB) Download ZIPPED TAR
2 Mapping between variants and structure files for our Test dataset Download CSV
3 531 model and experimental structure files for Training dataset (68 MB) Download ZIPPED TAR
4 Mapping between variants and structure files for our Training dataset Download CSV