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Missense3D-PTM^db is a comprehensive resource which allows users to explore millions of variants, post-translational modifications (PTMs), and topology information, if any, for the collection of canonical proteins within the human proteome (~20,000). Users can visualize these features on a 3D AlphaFold model for their protein of interest by simply providing (1) a gene name or UniProt ID and (2) a position within the canonical UniProt protein sequence.
Article now available https://doi.org/10.1016/j.jmb.2025.169595

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Find Protein Features

UniProt ID:

OR Gene Name:

Residue Position:

You can also choose from these examples to help you get started (click to apply) Uniprot ID:P05067 | Residue Position:198 Uniprot ID:P00533 | Residue Position:1162 Gene Name:INSR | Residue Position:1361 Gene Name:NPC1 | Residue Position:222